Difluoromethylene substituted prostaglandin derivatives

Details Difluoromethylene substituted prostaglandin derivatives Difluoromethylene substituted prostaglandin derivatives

C - Chemistry, Metallurgy

07

C

260/235.01

C07C 405/00 (2006.01) C07C 43/174 (2006.01) C07C 45/51 (2006.01) C07C 49/753 (2006.01) C07D 307/935 (2006.01) C07D 309/12 (2006.01) C07F 5/00 (2006.01) C07F 9/40 (2006.01)

Patent

CA 1041496

DIFLUOROMETHYLENE SUBSTITUTED PROSTAGLANDIN DERIVATIVES Abstract of the Disclosure Novel antimeric or racemic prostaglandin derivatives having a difluoromethylene group attached to the C-11,12 positions of the molecule, oxygenated functions at C-9 and C-15 and unsatura- tions at C-13 or at C-5 and C-13, which may be further substituted at C-15 by a methyl or ethyl group, the C-20 nor- or bisnor- derivatives and certain C-20 alkyl derivatives thereof, processes for the production of such compounds and novel and useful intermediates obtained thereby. Also included are the methyl esters of the carboxylic acid function and pharmaceutically acceptable salts thereof. These compounds possess prosta- glandin-like activities and thus are useful in the treatment of mammals, where prostaglandins are indicated.

179099

Affiliated with

Also associated with

Rating

Difluoromethylene substituted prostaglandin derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Difluoromethylene substituted prostaglandin derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Difluoromethylene substituted prostaglandin derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-609831