Difluoroprostaglandin derivatives and their use

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 405/00 (2006.01) A61K 31/557 (2006.01)

Patent

CA 2225761

A fluorine-containing prostaglandin derivative of the formula (1) (or a salt thereof) and a medicine containing it, particularly, a preventive or therapeutic medicine for an eye disease: Image wherein A is a vinylene group or the like, R1 is an aryloxyalkyl group or the like, R2 and R3 are hydrogen atoms or the like, and Z is OR4 (wherein OR4 is a hydrogen atom or an alkyl group) or the like.

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