C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
150/15.1
C12Q 1/00 (2006.01) C12Q 1/32 (2006.01) G01N 33/52 (2006.01)
Patent
CA 1312539
ABSTRACT A system for the digital quantitative colorimetric analysis of NAD(P)H and biological fluids and organic compounds that generate NAD(P)H when reacted with a specific dehydrogenase. An NAD(P)H-dependent chromogen reduction occurs, which results in a visible color change. A known quantity of a competing reactant for the NAD(P)H is used, which prevents the chromogen from reacting and changing color until the reactant is consumed, the quantity of which corresponds to the threshold concentration of the NAD(P)H or the compound reacting to generate NAD(P)H. Disposable devices and methods of use are also disclosed.
554476
Palmer John L.
Timmerman Marsha W.
Blake Cassels & Graydon Llp
Enzymatics Inc.
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