Dihydrobenzofuran derivatives and uses thereof

Details Dihydrobenzofuran derivatives and uses thereof Dihydrobenzofuran derivatives and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 307/85 (2006.01) A61K 31/343 (2006.01) A61P 25/00 (2006.01) C07D 307/81 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2604916

Compounds of formula (I) are described herein which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. Formula (I), or pharmaceutically acceptable salts thereof, wherein each of R1, R2, R3, R4, Rx, Ry, and n are as defined herein. Such compounds, and compositions thereof, are useful for treating a variety of central nervous system disorders such as schizophrenia.

L'invention concerne des composés de formule (I) qui sont des agonistes ou des agonistes partiels du sous-type 2C des récepteurs cérébraux de la sérotonine. Dans la formule représentant les composés, ou des sels acceptables sur le plan pharmaceutique de ceux-ci, R1, R2, R3, R4, Rx, Ry, et n ont la signification indiquée dans la description. Lesdits composés, et les compositions les comprenant, sont utiles pour le traitement de divers troubles du système nerveux central comme la schizophrénie.

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