Dihydrobenzofuranyl derivatives of ala-pro

C - Chemistry – Metallurgy – 07 – K

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530/5.06

C07K 5/06 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1183836

ABSTRACT Compounds of formula (I): (I) Image or a pharmaceutically acceptable salt thereof, wherein m is 0 to 3; n is 1 to 5; R1 is hydrogen, or C1-6 alkyl; R2 is hydrogen, C1-4alkyl, -(CH2)p-NH2 wherein p is 1 to 4, or -NHCOR,wherein R5 is C1-4 alkyl; R3 is hydrogen or C1-6 alkyl; R4 is C1-4alkyl, C1-4 alkoxy, halogen or CF3; and X is CH2 or S. having useful pharmacological activity, compositions containing them, and a process for their preparation.

398173

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