C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/34 (2006.01) A61K 31/404 (2006.01) A61P 7/10 (2006.01) A61P 9/12 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2478172
he present invention relates to methods of treating pathological disorders susceptible to steroid hormone nuclear receptor modulation, particularly congestive heart failure, comprising administering to a patient in need thereof an effective amount of a compound of the formula: I or a pharmaceutically acceptable salt thereof. In addition, the present invention provides novel pharmaceutical compounds of Formula I, including the pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions which comprise as an active ingredient a compound of Formula I.
L'invention concerne des procédés servant à traiter des troubles pathologiques par modulation du récepteur nucléaire de l'hormone stéroïde, en particulier, l'insuffisance cardiaque globale, ce qui consiste à administrer au patient une quantité efficace d'un composé représenté par la formule :I ou un de ses sels acceptables sur le plan pharmaceutique. Elle concerne, de plus, de nouveaux composés pharmaceutiques représentés par la formule I, y compris leurs sels acceptables sur le plan pharmaceutique, ainsi que des compositions pharmaceutiques contenant en tant qu'ingrédients actifs un composé représenté par la formule I.
Grese Timothy Alan
Jadhav Prabhakar Kondaji
Lander Peter Ambrose
Neel David Andrew
Steinberg Mitchell Irvin
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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