Dihydromocimycin from streptomyces ramocissimus

Details Dihydromocimycin from streptomyces ramocissimus Dihydromocimycin from streptomyces ramocissimus

C - Chemistry, Metallurgy

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C12P 19/44 (2006.01) A23K 1/17 (2006.01) A61K 31/435 (2006.01) A61K 31/44 (2006.01) C07D 405/14 (2006.01) C07D 491/04 (2006.01) C07G 11/00 (2006.01) C07H 7/00 (2006.01) C07H 7/06 (2006.01) C11D 9/14 (2006.01) C12P 17/16 (2006.01) C12P 17/18 (2006.01) C12P 19/26 (2006.01)

Patent

CA 1070630

ABSTRACT OF THE DISCLOSURE A new antibiotic (now called dihydromocimycin) being a yellow, salt-forming weak acid and its non-toxic, pharmaceutically acceptable salts produced by the microorganism Streptomyces ramocissimus or suitable mutants thereof. The antibiotic has antibacterial properties and has been found to be effective against Treponema dysentery, one of the most common swine diseases. Dihydromocimycin may also be converted into mocimycin, which is an antibiotic which possesses interesting growth- promoting properties when added to animal feed, by a dehydrogenation agent. The dehydrogenation may be carried out with selenium dioxide, preferably in the presence of an organic solvent.

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