Dihydropyridazones, their manufacture, and therapeutic...

Details Dihydropyridazones, their manufacture, and therapeutic... Dihydropyridazones, their manufacture, and therapeutic...

C - Chemistry, Metallurgy

07

D

260/264.7

C07D 237/04 (2006.01)

Patent

CA 1108614

O.Z. 32,647 ABSTRACT OF THE DISCLOSURE: 6-(p-Acylaminophenyl)-4,5-dihydropyridaz-3-ones of the formula I Image I where R1 is hydrogen or alkyl of 1 to 3 carbon atoms and R2, if R1 is hydrogen, is halogen-substituted alkyl of 3 to 6 carbon atoms or .beta.-haloethyl or, if R1 is alkyl of 1 to 3 carbon atoms, is halogen-substituted alkyl of 1 to 6 carbon atoms, their manu- facture, and therapeutlc agents which contain, as the active ingredient, a compound of the formula I, where R2 may also be halo- methyl or .alpha.-haloethyl if R1 is hydrogen. These compounds may be used as anti-hypertensive agents and for the prophylaxis and therapy of thrombo-embolic disorders.

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