Dihydropyridine-5-phosphonic acid cyclic ester

C - Chemistry – Metallurgy – 07 – F

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C07F 9/6574 (2006.01) A61K 31/675 (2006.01)

Patent

CA 1305149

ABSTRACT An optical isomer of a compound having the formula: (I) Image wherein the two methyl groups at 4- and 6-positions of the dioxaphosphorinane ring assume trans configurations to each other, which has a levo-rotatory angle of optical rotation attributable to the asymmetric carbon atom at 4-position of the dihydropyridine ring, and a pharmaceutically acceptable salt thereof.

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