Dihydropyridine compounds having simultaneous ability to...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/04 (2006.01) A61K 31/444 (2006.01) A61K 31/4709 (2006.01) A61K 31/501 (2006.01) A61K 31/505 (2006.01) A61P 9/00 (2006.01) C07D 211/90 (2006.01) C07D 213/85 (2006.01) C07D 235/00 (2006.01) C07D 237/04 (2006.01) C07D 239/00 (2006.01) C07D 401/12 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2501534

The present invention provides compounds that possess inhibitory activity against PDE-3 and L-type calcium channels. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine.

L'invention concerne des composés qui présentent une activité inhibitrice contre les canaux calciques de type PDE-3 et L. Cette invention porte aussi sur des compositions pharmaceutiques contenant ces composés et sur des procédés d'utilisation de ces composés afin de traiter les maladies cardio-vasculaires, les attaques, l'épilepsie, les troubles ophtalmiques ou la migraine.

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