Dihydropyridine derivatives, their production and use

Details Dihydropyridine derivatives, their production and use Dihydropyridine derivatives, their production and use

C - Chemistry, Metallurgy

07

D

167/211, 260/262

C07D 401/00 (2006.01) C07D 211/90 (2006.01) C07D 213/74 (2006.01) C07D 243/08 (2006.01) C07D 295/088 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1333487

Novel dihydropyridine derivatives and acid addition salts thereof which are of use as prophylactic or/and therapeutic drugs for cardiovascular diseases, said dihydropyridine derivatives having the formula Image Image [wherein R1, R2 and R3 are the same or different and each is alkyl, cycloalkyl or alkoxyalkyl; R4 and R5 are the same or different and each is hydrogen, halogen, nitro, trifluoromethyl, alkyl, cycloalkyl, alkoxy, cyano, alkoxycarbonyl or alkylthio; R6 is hydrogen, alkyl, cycloalkyl, aralkyl, aryl or a pyridyl; X is oxygen sulfur, vinylene, azomethine or a group of the formula Image or Image ; A is alkylene; Ar is aryl or a pyridyl; m is an integer of 1 to 3; n is an integer of 0 to 2].

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