C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/251
C07D 211/90 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 417/04 (2006.01) C07D 498/04 (2006.01)
Patent
CA 1278573
Abstract Title: "Dihydropyridines" Compounds of the formula:- Image ----(I) where R is an optionally substituted aryl or heteroaryl group; R1 and R2 are each independently C1-C4 alkyl or 2-methoxyethyl; and Y is -(CH2)n- where n is 2, 3 or 4, -CH2CH(CH3)- or -CH2C(CH3)2-; and their pharmaceutically acceptable salts. The compounds have utility as anti-ischaemic ant antihypertensive agents and as synthetic intermediates to other dihydropyridine calcium antagonists.
481320
Alker David
Campbell Simon Fraser
Cross Peter Edward
Pfizer Corporation
Smart & Biggar
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