Dihydropyridone amides as p2x7 modulators

Details Dihydropyridone amides as p2x7 modulators Dihydropyridone amides as p2x7 modulators

C - Chemistry, Metallurgy

07

D

C07D 211/86 (2006.01) A61K 31/4412 (2006.01) A61P 3/10 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2746561

Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.

L'invention concerne des composés de formule (I) ou leurs sels pharmaceutiquement acceptables, m, n, R1, R2, R3, R4 et R5 étant définis ici. Elle concerne également des procédés de préparation des composés et d'utilisation des composés pour le traitement de maladies associées au récepteur purinergique P2X7.

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