C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/44 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2745864
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4, R5 and R a are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
La présente invention concerne des composés de formule I ou leurs sels pharmaceutiquement acceptables, dans laquelle m, n, R1, R2, R3, R4, R5 et Ra sont tels que définis dans le présent document. La présente invention concerne en outre des procédés de fabrication des composés et d'utilisation des composés pour le traitement de maladies associées au récepteur purinergique P2X7.
Berger Jacob
Caroon Joan Marie
Krauss Nancy Elisabeth
Lopez-Tapia Francisco Javier
Walker Keith Adrian Murray
Borden Ladner Gervais Llp
F.hoffmann-La Roche Ag
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