C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/86 (2006.01) A61K 31/4412 (2006.01) A61K 31/4418 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2747925
Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4, R5 and R a are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
L'invention concerne des composés représentés par la formule (I) ou des sels pharmaceutiquement acceptables de ceux-ci m, n, R1, R2, R3, R4, R5 et Ra étant tels que définis dans la demande. L'invention concerne aussi des procédés de fabrication de ces composés et d'utilisation de ceux-ci pour traiter des maladies associées au récepteur purinergique P2X7.
Berger Jacob
Caroon Joan Marie
Lopez-Tapia Francisco Javier
Nitzan Dov
Walker Keith Adrian Murray
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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