C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/86 (2006.01) A61K 31/4422 (2006.01) A61K 31/47 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2745866
Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
La présente invention concerne des composés de formule (I) ou leurs sels pharmaceutiquement acceptables, dans laquelle m, n, R1, R2, R3, R4 et R5 sont tels que définis dans le présent document. La présente invention concerne en outre des procédés de fabrication des composés et d'utilisation des composés pour le traitement de maladies associées au récepteur purinergique P2X7.
Brotherton-Pleiss Christine E.
Caroon Joan Marie
Lopez-Tapia Francisco Javier
Nitzan Dov
Walker Keith Adrian Murray
Borden Ladner Gervais Llp
F.hoffmann-La Roche Ag
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