Dihydroquinone and dihydronaphthridine inhibitors of jnk

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 215/48 (2006.01) A61K 31/4375 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61P 3/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 413/04 (2006.01) C07D 471/04 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2686385

Compounds of formula I or a pharmaceutically acceptable salt thereof are effective modulators of JNK: (formula) wherein X, Y, Z, R4, R5, R6 and R7 are as defined herein.

L'invention concerne des composés représentés par la formule I ou un sel pharmaceutiquement acceptable de ceux-ci, qui constituent des modulateurs efficaces de JNK: X, Y, Z, R4, R5, R6 et R7 étant définis dans le descriptif.

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