Dihydrothieno pyrimidines as akt protein kinase inhibitors

Details Dihydrothieno pyrimidines as akt protein kinase inhibitors Dihydrothieno pyrimidines as akt protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2656364

The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula (I): Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

L'invention concerne des composés comprenant les énantiomères résolus, les diastéréoisomères, les solvates et les sels pharmaceutiquement acceptables de ceux-ci, représentés par la Formule (I) : L'invention concerne également des procédés d'utilisation de cette invention comme inhibiteurs de l'AKAT protéine kinase et pour le traitement de maladies hyperprolifératives telles que le cancer.

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