Dihydroxynaphthalene derivatives

Details Dihydroxynaphthalene derivatives Dihydroxynaphthalene derivatives

C - Chemistry, Metallurgy

07

C

167/254, 167/262

C07C 65/24 (2006.01) A61K 31/19 (2006.01) C07C 43/225 (2006.01) C07C 49/84 (2006.01) C07C 65/40 (2006.01) C07C 69/614 (2006.01) C07C 69/90 (2006.01)

Patent

CA 2010334

RAN 4070/76 Abstract Dihydroxynaphthalene derivatives of the formula Image I in which R1 is hydrogen, lower alkyl or benzyl, R2 is hydrogen, hydroxy or lower alkanoyloxy, R3 is hydrogen or lower alkyl, R4 is hydrogen or halogen, R5 is hydrogen, acyl, methyl or benzyl, m is 0 or 1, and n is an integer from 2 to 10, and salts thereof with a pharmaceutically acceptable base when R1 is hydrogen are useful in the treatment of inflammatory diseases. They are prepared by reacting corresponding p-hydroxybenzoic acid derivatives with corresponding dihydroxynaphthalene derivatives.

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