C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/437 (2006.01) A61K 31/4427 (2006.01) A61K 31/4436 (2006.01) A61P 31/18 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2650382
This disclosure provides compounds of Formula I, or pharmaceutically acceptable salts thereof; (I) wherein: A is selected from the group consisting of: (II) having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with diketo piperazine and piperadine derivatives that possess unique antiviral activity. More particularly, the present disclosure relates to compounds useful for the treatment of HTV and AIDS.
La présente invention concerne des composés présentant des propriétés médicamenteuses et biologiques, ainsi que les compositions pharmaceutiques les incluant et leur méthode d'utilisation. En particulier, la présente invention concerne des dérivés de dicéto-pipérazine et pipéridine présentant une activité antivirale unique. Plus particulièrement, la présente invention concerne des composés pouvant être employés dans le traitement du VIH et du SIDA.
Carini David J.
Han Ying
Kadow John F.
Meanwell Nicholas A.
Regueiro-Ren Alicia
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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