Diltiazem controlled release formulation and method of...

A - Human Necessities – 61 – K

Patent

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A61K 9/26 (2006.01) A61K 31/554 (2006.01)

Patent

CA 2617351

A controlled release diltiazem dosage formulation comprising a plurality of diltiazem pellets and a gel-forming material where the time of maximum diltiazem blood plasma levels occurs more than 8 hours after administration and preferably more than 10 hours after administration.

L'invention concerne une formulation à libération contrôlée de doses de diltiazem qui renferme une pluralité de pellets ainsi qu'un matériau gélifiant, les concentrations maximales de diltiazem dans le plasma sanguin se produisant 8 heures, et préférablement plus de 10 heures, après administration.

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