Dimeric cationic lipids on dicystine basis

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/068 (2006.01) A61K 48/00 (2006.01) C07C 237/22 (2006.01) C07C 323/60 (2006.01) C12N 15/87 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2281915

The present invention provides novel dimeric cationic lipids. The present invention further provides compositions of these lipids with anionic or polyanionic macromolecules, methods for interfering with protein expression in a cell utilizing these compositions and a kit for preparing the same.

La présente invention concerne de nouveaux lipides cationiques dimères. La présente invention concerne également des compositions de ces lipides avec des macromolécules anioniques ou polyanioniques, des méthodes d'interférence avec une expression de protéines dans une cellule faisant appel à ces compositions, ainsi qu'une trousse destinée à la préparation de ces lipides.

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