Dimethylamine benzoate or p-anisate catalysed process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/90 (2006.01) C07C 201/12 (2006.01) C07C 205/56 (2006.01)

Patent

CA 2215837

A method for the preparation of 4-(nitrophenyl)-dihydropyridines, by reacting a benzaldehyde with an acetoacetate and subsequently reacting the resulting benzylidene derivative with an enamine derivative. Both reactions are catalyzed by dimethylamine benzoate or p--anisate.

Un procédé de préparation de 4-(nitrophényl)-dihydropyridines, consiste à faire réagir un benzaldéhyde avec un acétoacétate et ensuite à faire réagir le dérivé de benzylidène résultant avec un dérivé d'énamine. Le benzoate ou le p-anisate de diméthylamine servent de catalyseur pour les deux réactions.

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