C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/220, 260/242
C07D 487/04 (2006.01) A61K 31/505 (2006.01)
Patent
CA 2006354
4918N ABSTRACT A novel glycol of a triazolopyrimidine diuretic which is a metabolite and which exhibits fewer cardiotoxic side effects than the parent compound, but with no decrease in diuretic activity. The invention further provides for compositions incorporating the metabolite, and methods of its use as well as pharmaceutically acceptable salts thereof.
Burton Earl G.
Chengelis Christopher P.
Walsh Gerald M.
G.d. Searle & Co.
Osler Hoskin & Harcourt Llp
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