Diol sulfonamide and sulfinyl renin inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 233/64 (2006.01) A61K 31/18 (2006.01) A61K 31/395 (2006.01) C07C 311/33 (2006.01) C07C 311/46 (2006.01) C07C 311/47 (2006.01) C07C 311/48 (2006.01) C07D 213/38 (2006.01) C07D 213/81 (2006.01) C07D 233/54 (2006.01) C07D 263/32 (2006.01) C07D 277/30 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07F 9/645 (2006.01)

Patent

CA 2023936

HA487 ABSTRACT Diol Sulfonamide And Sulfinyl Renin Inhibitors Compounds of the formula Image wherein Z is SO or SO2 possess renin inhibition activity and are useful in treating hypertension and other diseases where the reduction of the levels of circulating angiotensin II are beneficial.

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