Dioxolobenzisoxazole derivatives and process for preparing...

Details Dioxolobenzisoxazole derivatives and process for preparing... Dioxolobenzisoxazole derivatives and process for preparing...

C - Chemistry, Metallurgy

07

D

167/235, 260/298

C07D 498/04 (2006.01) A61K 31/42 (2006.01)

Patent

CA 1269984

Abstract Dioxolobenzisoxazole derivatives of the formula Image wherein R1 is a phenyl group which may be substituted with a halogen atom, a lower alkyl group having 1-3 carbon atoms or a lower haloalkyl group, or a thienyl group, R2 is a hydrogen atom or a lower alkyl group having 1-4 carbon atoms; and X and Y which may be the same or different represent a hydrogen atom or a halogen atom, as well as non-toxic salts thereof when R2 is a hydrogen atom, a process for preparing the same and a pharmaceutical composition containing the same; the derivatives have diuretic and uricosuric activities and, therefore, are useful as a drug for treating hyperuricemia or hypertension.

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