Dioxy octahydrobenzocycloheptapyridoisoquinoline derivatives

C - Chemistry – Metallurgy – 07 – D

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167/231, 260/271

C07D 455/03 (2006.01) A61K 31/47 (2006.01)

Patent

CA 1249826

ABSTRACT OF THE DISCLOSURE 2,3,4,4a,8,9,13b,14-Octahydro-1H-benzo[6,7] cyclohepta[1,2,3-de]- pyrido[2,1-a] isoquinoline derivatives, characterized by having two adjacent oxy substituents at positions 5 and 6, 6 and 7 or 11 and 12 are disclosed. The derivatives are central nervous system depressants. Methods for their pre- paration and use are described.

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