Dipeptide derivatives, process for their production and...

Details Dipeptide derivatives, process for their production and... Dipeptide derivatives, process for their production and...

C - Chemistry, Metallurgy

12

P

C12P 21/02 (2006.01) A61K 38/05 (2006.01) C07K 5/065 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2202379

Compounds of formula (I) in which R1 and R2 are hydroxy or an acyloxy group and R3 is hydrogen, where R2 and R3 together may also signify a valency line. Process for their production from cyanobacteria of the Oscillatoria agardhii genus, and medicaments containing said compounds with a thrombin and trypsin inhibiting action.

L'invention concerne des composés de la formule (I) dans laquelle R?1¿ et R?2¿ désignent hydroxy ou un groupe acyloxy et R?3¿ désigne hydrogène, R?2¿ et R?3¿ pouvant également désigner conjointement un trait de valence. L'invention concerne également leurs procédés de préparation à partir de bactéries cyano de type Oscillatoria agardhii, ainsi que des médicaments qui contiennent ces composés, à effet inhibiteur de la thrombine et de la trypsine.

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