Dipeptide inhibitors for the blood-clotting factor xa

Details Dipeptide inhibitors for the blood-clotting factor xa Dipeptide inhibitors for the blood-clotting factor xa

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01) A61K 38/04 (2006.01) C07C 257/00 (2006.01) C07C 257/18 (2006.01) C07C 259/18 (2006.01) C07K 5/068 (2006.01)

Patent

CA 2412181

The invention relates to derivatives of amidino-benzylamine, especially derivatives of 4-amidino-benzylamine, with two bonded amino acids. These derivatives represent a novel group of highly active and very selective F Xa- inhibitors for treating cardiovascular diseases and thrombotic events.

Dérivés d'amidino-benzylamine, en particulier de 4-amidino-benzylamine, avec deux acides aminés liés, qui constituent un nouveau groupe d'inhibiteurs hautement actifs et très sélectifs du facteur Xa pour le traitement des maladies cardio-vasculaires et des accidents thrombotiques.

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