Dipeptides and process

C - Chemistry – Metallurgy – 12 – P

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530/5.06, 99/140

C12P 21/02 (2006.01) A23L 1/236 (2006.01) C07K 5/072 (2006.01) C07K 5/075 (2006.01)

Patent

CA 1338633

Synthesis of phenylserine ester a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and b) via methyl benzoylacetate. Synthesis of hydroxy-aspartame or derivative by enzymatic coupling of phenylserine or derivative with aspartic acid or derivative. Hydrogenation of the coupled product to give as final product aspartame or analog with related processes and products.

520855

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