Dipeptidyl peptidase inhibitors for the treatment of diabetes

Details Dipeptidyl peptidase inhibitors for the treatment of diabetes Dipeptidyl peptidase inhibitors for the treatment of diabetes

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/445 (2006.01) A61K 31/4453 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61K 31/517 (2006.01) A61K 31/5375 (2006.01) C07D 209/14 (2006.01) C07D 211/32 (2006.01) C07D 213/36 (2006.01) C07D 217/22 (2006.01) C07D 239/52 (2006.01) C07D 239/86 (2006.01) C07D 241/04 (2006.01) C07D 265/30 (2006.01) C07D 275/06 (2006.01) C07D 295/185 (2006.01) C07D 319/18 (2006.01) C07D 333/20 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01) C07

Patent

CA 2450475

Compounds having Formula (I), including pharmaceutically acceptable salts and prodrugs thereof are inhibitors of the dipeptidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus.

L'invention concerne des composés de formule (I), contenant des sels pharmaceutiquement acceptables et des promédicaments de ceux-ci. Ces composés sont des inhibiteurs de l'enzyme dipeptidyl peptidase-IV (DP-IV) et s'utilisent dans le traitement de maladies et d'états pathologiques véhiculés par DP-IV, notamment le diabète sucré non insulino-dépendant.

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