Dipeptidyl peptidase inhibitors for the treatment of diabetes

Details Dipeptidyl peptidase inhibitors for the treatment of diabetes Dipeptidyl peptidase inhibitors for the treatment of diabetes

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 38/55 (2006.01) A61K 45/00 (2006.01) C07D 207/16 (2006.01) C07D 207/26 (2006.01) C07D 207/46 (2006.01) C07D 277/06 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/06 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2450579

Compounds having Formula I, including pharmaceutically acceptable salts and prodrugs thereof: (Formula I) are inhibitors of the dipep tidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus.

L'invention concerne des composés de formule (I), comprenant des sels pharmaceutiquement acceptables et des promédicaments pharmaceutiquement acceptables de ceux-ci. (I) Ces composés, qui inhibent l'enzyme dipeptidyle peptidase (DP-IV), s'avèrent utiles dans le traitement de maladies et d'états associés au DP-IV, tels que le diabète non insulino-dépendant.

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