Dipeptidyl peptidase inhibitors for the treatment or...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/40 (2006.01) A61K 31/4178 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/4436 (2006.01) A61K 31/4535 (2006.01) C07D 207/09 (2006.01) C07D 207/16 (2006.01) C07D 277/04 (2006.01) C07D 277/06 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2441092

The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

La présente invention concerne des composés qui sont des inhibiteurs de l'enzyme peptidase IV dipeptidyl (inhibiteurs DP-IV) et qui conviennent pour le traitement ou la prévention de maladies dans lesquelles cette enzyme peptidase IV dipeptidyl est impliquées, telles que le diabète et en particulier le diabète de type 2. Cette invention concerne aussi des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés et de ces compositions dans la prévention ou le traitement de ces maladies dans lesquelles l'enzyme peptidase IV dipeptidyl est impliquée.

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