C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/4725 (2006.01) A61K 31/4985 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) C07D 401/06 (2006.01) C07D 413/06 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2602248
The present invention relates to novel compounds, having an optionally substituted lactam ring, and having the following general structure: (see above formula) The novel compounds have excellent inhibitory activity against Dipeptidyl Peptidase-IV. The invention also relates to methods of preparing the novel compounds and pharmaceutical compositions containing the novel compounds as an active ingredient.
La présente invention concerne de nouveaux composés présentant une activité inhibitrice satisfaisante vis-à-vis de la Dipeptidylpeptidase-IV (DPP-IV), ainsi que des méthodes de synthèse desdits composés et des préparations pharmaceutiques contenant lesdits composés au titre de principe actif.
Bu Seong Cheol
Han Hee Oon
Hong Sang Yong
Hur Gwong-Cheung
Kim Geun Tae
Gowling Lafleur Henderson Llp
Lg Life Sciences Ltd.
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