Diphenyl compounds which inhibit arachidonic acid...

Details Diphenyl compounds which inhibit arachidonic acid... Diphenyl compounds which inhibit arachidonic acid...

A - Human Necessities

61

K

A61K 31/05 (2006.01) A61K 31/055 (2006.01) A61K 31/06 (2006.01) A61K 31/085 (2006.01) A61K 31/10 (2006.01)

Patent

CA 2050569

Pharmaceutical compositions, which comprise a compound of the general formula I (see formula I) in which X is oxygen, sulfur or -CH2-, Y is chlorine or bromine, Z is an SO2H, NO2 or C1-C4alkyl radical, r is a number from 0 to 3, o is a number from 0 to 3, p is the number 0 or 1, m is the number 1 or 2 and n is the number 0 or 1, have having a lipoxygenase- and prostaglandin H synthase-inhibiting action. The compositions are useful in particular for the local (topical) or inhalative treatment of inflammatory, allergic and spasmolytic diseases, as well as psoriasis, bronchial asthma and diseases with disturbances in cell proliferation.

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