C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 205/08 (2006.01) A61K 31/397 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2548410
Compounds of formula (XV): [Chemical formula should be inserted here. Please see paper copy] (XV) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
L'invention concerne des composés de formule (XV) (dans laquelle de nombreux groupes sont spécifiés dans la description), ainsi que leurs sels pharmaceutiquement acceptables, des solvates, des solvates desdits sels et leurs promédicaments. L'invention concerne également leur utilisation en tant qu'inhibiteurs d'absorption du cholestérol dans le traitement de l'hyperlipidémie. L'invention concerne, en outre, des procédés de fabrication des composés ainsi que des compositions pharmaceutiques les contenant.
Alenfalk Susanne
Dahlstroem Mikael
Hunegnaw Fana
Karlsson Staffan
Lemurell Malin
Astrazeneca Ab
Fetherstonhaugh & Co.
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