Diphenylbutyl-1-acylpiperazines

Details Diphenylbutyl-1-acylpiperazines Diphenylbutyl-1-acylpiperazines

C - Chemistry, Metallurgy

07

D

260/267.5, 260/2

C07D 295/18 (2006.01) C07D 295/185 (2006.01) C07D 295/192 (2006.01) C07D 405/06 (2006.01)

Patent

CA 1173832

19 ABSTRACT Compounds having the general formula Image I wherein R' is alkyl straight or branch chained having from 2 to 10 carbon atoms, preferably 2-3 carbon atoms, cyclo- alkyl having from 3 to 8 carbon atoms, preferably 3 carbon atoms, aralkyl having from 7 to 9 carbon atoms or phenyl unsubstituted or substituted by one to three F, Cl,Br, lower alkyl having from 1 to 5 carbon atoms, lower alkoxy having from 1 to 5 carbon atoms, alkylenedioxy having from 1 to 3 carbon atoms, -CF3 or -CN substituents and pharma- ceutically acceptable salts thereof and processes for their preparation. Pharmaceutical compositions containing said compounds. Methods of treatment of humans and animals by such compounds and composition. The compounds have valuable anti-aggressive, antipsychotic and antidepressive properties and exhibit analgetic properties.

379765

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