Diphenylurea derivatives

Details Diphenylurea derivatives Diphenylurea derivatives

C - Chemistry, Metallurgy

07

C

167/265, 260/545

C07C 275/28 (2006.01) A61K 31/17 (2006.01) C07C 275/30 (2006.01) C07C 275/34 (2006.01) C07C 335/16 (2006.01)

Patent

CA 2018848

Abstract: Novel diphenylurea derivatives represented by the following formula (I): Image (I) wherein R1 is an alkyl group of 5 to 18 carbon atoms, each of R2 and R3 is independently an alkyl group of 1 to 5 carbon atoms, an alkoxy group of 1 to 5 carbon atoms or a halogen atom, R4 is hydrogen atom, an alkyl group of 1 to 5 carbon atoms, an alkoxy group of 1 to 5 carbon atoms or a halogen atom, and X is oxygen atom or sulfur atom, are provided. The compounds are potent in reducing the cholesterol level in serum, and useful for treating hyperlipemia and atherosclerosis. 36

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