Diphenylurea derivatives and their use as chloride channel...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 271/07 (2006.01) A61K 31/4245 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2646336

The present invention relates to novel diphenylurea derivatives of formula (I) useful as chloride channel blockers or BKCa channel modulators. In other aspects the invention relates to the use of these compounds in a method for therapy, and to pharmaceutical compositions comprising the compounds of the invention.

La présente invention concerne de nouveaux dérivés de diphénylurée de formule (I) qui peuvent être employés en tant qu'agents bloquant le canal chlorure ou modulateurs du canal BKCa. Dans d'autres aspects, l'invention concerne l'utilisation de ces composés dans une méthode thérapeutique, ainsi que des compositions pharmaceutiques incluant les composés selon l'invention.

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