Diphtheria toxin receptor-binding region

Details Diphtheria toxin receptor-binding region Diphtheria toxin receptor-binding region

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 39/05 (2006.01) C07K 14/34 (2006.01) C07K 19/00 (2006.01) C12N 9/12 (2006.01) C12N 15/31 (2006.01) C12N 15/54 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2135052

2135052 9321769 PCTABS00027 The invention features a polypeptide consisting of amino acids 379-535 of diphtheria toxin, and portions thereof. This region, shown by X-ray crystallographic analysis to comprise the receptor binding domain of diphtheria toxin, is used as an immunogen and clinical therapeutic against diphtheria.

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