Dipyrazoles as central nervous system agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 231/22 (2006.01) A61K 31/455 (2006.01) A61P 25/00 (2006.01) C07D 231/26 (2006.01)

Patent

CA 2601098

The present invention is directed to novel dipyrazole compounds compositions, or the pharmaceutically acceptable salts, stereoisomers, tautomers, or solvates thereof. Novel compounds include those of formula (I). The compounds of this invention modulate AMPA and NMDA receptor function, and therefore are useful as pharmaceutical agents, especially for the treatment of neuropsychiatric disorders.

La présente invention porte sur de nouveaux composés de dipyrazole, et sur leurs sels acceptables d'un point de vue pharmaceutique, sur des stéréoisomères, des tautomères ou des solvates de ceux-ci. L'invention porte également sur de nouveaux composés comprenant ceux de la formule (I). Les composés de cette invention modulent la fonction des récepteurs AMPA et NMDA et, par conséquent, sont utiles comme agents pharmaceutiques, notamment dans le traitement de troubles neuropsychiatriques.

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