Direct assay of cholesterol in skin samples removed by tape...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/60 (2006.01) A61B 10/00 (2006.01) C12Q 1/26 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2465427

Skin cholesterol is measured by applying an adhesive tape onto a selected area of the skin to adhere the tape to the selected skin area and stripping the tape off the selected skin area to obtain a sample representative of the outer stratum corneum layer of the skin, the sample adhering to the tape so as to have exposed skin constituents. The sample is assayed using a detector reagent that specifically binds to cholesterol and in addition has an indicator component that allows quantitation of the amount of cholesterol present in the exposed skin constituents.

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