Direct compression formulation and process

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 9/20 (2006.01) A61K 31/195 (2006.01) A61K 31/40 (2006.01) A61K 31/4439 (2006.01) A61K 47/00 (2006.01) C07D 207/00 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2593359

This invention relates to tablets especially tablets formed by direct compression of a dipeptidylpeptidase IV (DPP-IV) inhibitor compound, a process for the preparation thereof, to new pharmaceutical formulations , and new tableting powders comprising DPP-IV inhibitor formulations capable of being directly compressed into tablets. The invention relates further to a process for preparing the tablets by blending the active ingredient and specific excipients into the new formulations and then directly compressing the formulations into the direct compression tablets. The invention also relates to vildagliptin particle size distribution and a new crystal form of vildagliptin particularly adapted for the preparation of improved tablets and other pharmaceutical compositions.

Cette invention concerne des comprimés, en particulier des comprimés réalisés par compression directe d'un composé inhibiteur de la dipeptidylpeptidase IV (DPP-IV), un procédé de préparation afférent, de nouvelles formulations pharmaceutiques et de nouvelles poudres de fabrication de comprimés renfermant des formulations à base d'inhibiteur de DPP-IV capables d'être directement préparées sous forme de comprimés. L'invention concerne également un procédé de préparation des comprimés qui consiste à mélanger l'ingrédient actif avec des excipients spécifiques dans les nouvelles formulations puis à préparer directement les formulations dans les comprimés à compression directe. L'invention concerne également une distribution granulométrique de vildagliptine et une nouvelle forme cristalline de vildagliptine convenant particulièrement à la préparation de comprimés améliorés ainsi que d'autres compositions pharmaceutiques.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Direct compression formulation and process does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Direct compression formulation and process, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Direct compression formulation and process will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1836621

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.