Direct measurements of arterial pressure decoupling

A - Human Necessities – 61 – B

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A61B 5/021 (2006.01) A61B 5/026 (2006.01) A61B 5/0295 (2006.01)

Patent

CA 2755130

Methods for monitoring central-to-peripheral arterial pressure decoupling, i.e., hyperdynamic or vasodilation conditions are described. These methods involve the comparison of parameters such as impedance, compliance, and pressure that can be determined from flow and pressure measurements at central aortic and peripheral arterial locations. The relationship between the parameters at the central aortic and peripheral arterial locations provides an indication of central-to-peripheral arterial pressure decoupling. These methods can be alert a user that a subject is experiencing central-to-peripheral arterial pressure decoupling, which can enable a clinician to appropriately provide treatment to the subject.

Cette invention concerne des méthodes permettant de surveiller le découplage de la pression artérielle centrale-à-périphérique, c'est-à-dire les conditions hyperdynamiques ou de vasodilatation. Ces méthodes impliquent la comparaison de paramètres tels que l'impédance, la compliance, et la pression qui peuvent être déterminés à partir de mesures de débit et de pression à des positions aortiques centrales et artérielles périphériques. La relation entre les paramètres à ces positions aortiques centrales et artérielles périphériques fournit une indication sur le découplage de la pression artérielle centrale-à-périphérique. Ces méthodes peuvent alerter un utilisateur qu'un sujet est en train de subir un découplage de la pression artérielle centrale-à-périphérique, ce qui permet à un clinicien d'administrer le traitement approprié au sujet.

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