C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12N 1/00 (2006.01)
Patent
CA 2508359
The present invention provides methods for detecting a target nucleic acid molecule in a sample that comprises nucleic acid molecules of higher biological complexity than that of amplified nucleic acid molecules. In particular, the present invention provides methods and probes for detecting a single nucleotide polymorphism (SNP) in a sample that comprises nucleic acid molecules of higher biological complexity than that of amplified nucleic acid molecules.
La présente invention se rapporte à des procédés permettant de détecter une molécule d'acide nucléique cible dans un échantillon qui contient des molécules d'acide nucléique dont la complexité biologique est supérieure à celle de molécules d'acide nucléique amplifiées. En particulier, l'invention concerne des procédés et des sondes permettant de détecter un polymorphisme à nucléotide unique (SNP) dans un échantillon qui contient des molécules d'acide nucléique dont la complexité biologique est supérieure à celle de molécules d'acide nucléique amplifiées.
Bao Yijia P.
Hetzel Susan R.
Marla Sudhakar S.
Muller Uwe R.
Storhoff James J.
Gowling Lafleur Henderson Llp
Nanosphere Inc.
LandOfFree
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