C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) C07K 14/245 (2006.01) C07K 14/475 (2006.01) C07K 14/575 (2006.01) C12N 9/00 (2006.01) C12N 9/04 (2006.01) C12N 9/12 (2006.01) C12N 15/10 (2006.01) C12N 15/70 (2006.01) C12N 15/90 (2006.01) C12P 7/18 (2006.01)
Patent
CA 2372556
The present invention provides methods for directing the evolution of microorganisms comprising the use of mutator genes and growth under conditions of selective pressure. The method discloses mutator genes which can be used in the methods of the present invention and provides ATCC deposits which exemplify the evolved microorganisms produced by the methods.
La présente invention porte sur des procédés visant à diriger l'évolution de micro-organismes et consistant à utiliser des gènes mutateurs et des facteurs de croissance dans des conditions de pression sélective. Ce procédé décrit des gènes mutateurs pouvant être utilisés dans cette invention, et les dépôts ATCC expliquent l'évolution des micro-organismes obtenus selon ces procédés.
Liu Amy D.
Schellenberger Volker
Selifonova Olga V.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Genencor International Inc.
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