Directly pressed aliskiren tablets

Details Directly pressed aliskiren tablets Directly pressed aliskiren tablets

A - Human Necessities

61

K

A61K 9/20 (2006.01) A61K 9/16 (2006.01) A61K 31/165 (2006.01)

Patent

CA 2730112

The invention relates to pharmaceutical compositions which contain the active agent Aliskiren and are suitable for the production of tablets by dry pressing, so that prior wet granulation can be obviated. The invention also relates to tablets which can be obtained by dry pressing of these pharmaceutical compositions and to a method for producing these tablets. The invention furthermore relates to the use of the novel pharmaceutical compositions and tablets for treating hypertension and illnesses associated therewith.

L'invention concerne des compositions pharmaceutiques qui contiennent le principe actif aliskirène et sont adaptées à la fabrication de comprimés par compression à sec, une granulation préalable par voie humide étant ainsi inutile. L'invention concerne en outre des comprimés pouvant être obtenus par compression à sec de ces compositions pharmaceutiques, ainsi qu'un procédé de fabrication de ces comprimés. L'invention concerne par ailleurs l'utilisation de ces nouvelles compositions pharmaceutiques et de ces nouveaux comprimés pour traiter l'hypertonie et les maladies associées à l'hypertonie.

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