Disaccharide derivatives

C - Chemistry – Metallurgy – 07 – H

Patent

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260/230.58

C07H 13/06 (2006.01) C07H 11/04 (2006.01) C07K 14/525 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1243311

ABSTRACT OF THE DISCLOSURE Disaccharide derivatives represented by the formula (I): (I) Image wherein R1CO- and R2CO- each represents a residue of a straight chain fatty acid having from 8 to 20 carbon atoms and having a hydroxyl group at the 3-position thereof; R3CO- and R4CO- each represents a residue of a straight chain fatty acid having from 8 to 20 carbon atoms; and m and n each represents an integer of from 8 to 12, and the salts thereof. The compounds exhibit biological activities equal to or higher than those of natural lipid A. Also, the compounds of this invention are very useful as standard reagent for determination of endotoxin in the samples to be tested.

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