G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) G01N 33/15 (2006.01) G01N 33/557 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2469196
Methods to screen antibodies against an antigen, categorize them according to the epitope they recognize, and rank them according to their binding affinities, thereby providing a method to rapidly and efficiently identify antibodies having potential usefulness in therapeutic products are described. Also described are methods of evaluating antibodies to determine their potential usefulness in therapeutic products.
L'invention concerne des méthodes destinées à cribler des anticorps contre un antigène, les catégoriser selon le site antigénique qu'ils reconnaissent, et les classer selon leurs affinités de liaison, tout en appliquant une méthode d'identification rapide et efficace des anticorps potentiellement utile dans des produits thérapeutiques. L'invention concerne également des méthodes d'évaluation des anticorps destinée déterminer leur utilité potentielle dans des produits thérapeutiques.
Babcook John
Davis Geoff
Gallo Michael
Green Larry
Jia Xiao-Chi
Abgenix Inc.
Smart & Biggar
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