C - Chemistry – Metallurgy – 12 – M
Patent
C - Chemistry, Metallurgy
12
M
C12M 1/34 (2006.01) B81C 1/00 (2006.01) C12M 1/42 (2006.01) C12Q 1/00 (2006.01) C40B 60/00 (2006.01) G01N 21/01 (2006.01) G01N 21/77 (2006.01)
Patent
CA 2710828
The present disclosure relates to the fields of microchips with microfluidic optical chambers with enhanced Raman surfaces for multiplexed optical spectroscopy. Embodiments of the present invention allow for ultra small sample volume, as well as high detection speed and throughput, as compared to conventional cuvettes or devices used in optical spectroscopy. Particular embodiments relate to scientific and medical research, the diagnosis of diseases such as cancer, cardiovascular disease, diabetes, etc., and specifically to the detection of biomarkers and determination of protein activity with relevant scientific and medical applications.
La présente invention se rapporte aux domaines des micropuces à chambres optiques microfluidiques comportant des surfaces Raman améliorées pour une spectroscopie optique multiplex. Des modes de réalisation de la présente invention permettent d'utiliser des échantillons d'un volume infime, et offrent une vitesse et un débit de détection plus élevés que ceux des cuvettes ou des dispositifs classiques utilisés en spectroscopie optique. Certains modes de réalisation concernent plus particulièrement la recherche scientifique et médicale, le diagnostic de maladies telles que le cancer, les maladies cardio-vasculaires, le diabète, etc., et en particulier la détection de biomarqueurs et la détermination d'une activité protéique au moyen d'applications scientifiques et médicales appropriées.
Chen Zhongzhong
Jiang Kejun
Jiang Li
Shen Pao-Lin
Dynamic Throughput Inc.
Fetherstonhaugh & Co.
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